We developed EVOFLUx, a stochastic mathematical modelling and Bayesian inference framework, to simulate how clonal evolution quantitatively determines fCpG methylation values and enable inference of ...
Phylogenetic inference seeks to reconstruct the evolutionary history of organisms by analysing genetic, morphological or genomic data to infer branching patterns and divergence times. Central to this ...
In a recent study published in Nature Genetics, a group of researchers advanced variant effect prediction across the human proteome by integrating deep evolutionary signals with human population ...
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