Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...
RNA structure is critical for multiple steps in gene regulation. However, how the structures of transcripts differ both within and between individual cells is unknown. Here we develop a SHAPE-inspired ...
sc-SPORT offers a way to probe RNA structure at the single-cell level. It reveals cell-to-cell heterogeneity in RNA folding. Previous work on RNA structure in diverse organisms has connected RNA ...
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