The orbitofrontal cortex (OFC), a subsection of the brain's frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions ...

As humans and other animals navigate their surroundings and experience different things, their brain creates so-called cognitive maps, which are internal representations of environments or tasks.

New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood ...

The orbitofrontal, posterior parietal, and insular cortices are sites of higher-order cognitive processing implicated in a wide range of behaviours, including working memory, attention guiding, ...

A new study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation and decision making. By Priyanka Runwal Researchers have for the first ...

Depression imposes a major global socioeconomic burden, and current pharmacotherapies face several limitations, including slow efficacy, adverse effects, and non-response rates of up to 55%, ...

Functional constipation (FCon) is a prevalent common functional gastrointestinal disorders (FGIDs) frequently linked to mental and psychological disorders. Although previous studies have demonstrated ...