Nature

Prostate cancer grading: a decade after the 2005 modified system

Donald F Gleason in 1966 created a unique grading system for prostatic carcinoma based solely on the architectural pattern of the tumor. 1, 2 Another innovative aspect of this system was, rather than ...
Nature

Integrating tertiary Gleason pattern 5 into the ISUP grading system improves prediction of biochemical recurrence in radical prostatectomy patients

Gleason score is one the most important prognostic factors for prostate cancer. However, the original Gleason score has several issues to be resolved. For example, Gleason score 7 cases involve ...
ascopubs.org

Automated Renal Cancer Grading Using Nuclear Pleomorphic Patterns

Reannotation and Analysis of Clinical and Chemotherapy Outcomes in the Ovarian Data Set From The Cancer Genome Atlas Nuclear pleomorphic patterns are essential for Fuhrman grading of clear cell renal ...
GEN

AI Improves Grading Tumor Patterns and Subtypes of Lung Cancer

Currently, lung adenocarcinoma requires pathologist’s visual examination of lobectomy slides to determine the tumor patterns and subtypes. This classification has an important role in prognosis and ...