Adeno-associated virus (AAV) vector-based gene therapy is potentially curative for various genetic diseases; however, the development of a scalable purification method for full-genome AAV vectors ...

Creating analytical tools that support the advancement of knowledge can often come about through the integration of existing information and techniques, theoretical and practical, directed toward a ...

Retinal pigment epithelial (RPE) cell dysfunction and death are characteristics of age-related macular degeneration. A promising therapeutic option is RPE cell transplantation. Development of clinical ...

Researchers at Queen’s University in Kingston, Ontario, Canada, are developing an alternative to nickel-nitrilotriacetic acid (Ni-NTA) to purify recombinant proteins. Because it uses common ...

Water is perhaps Earth's most critical natural resource. Given increasing demand and increasingly stretched water resources, scientists are pursuing more innovative ways to use and reuse existing ...

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals. Scientists at the Technical University of ...

Plasmodium vivax is the most common parasite that causes malaria in Asia and South America. It preferentially infects an immature red blood cell that accounts for only 1–2% of circulating blood. The ...

The antibodies used in diagnostic techniques are often generated in vivo, when an animal is injected with a specific antigen from another species. The animal's immune system responds by producing ...

Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and ...

Rice University researchers have developed an innovative solution to a pressing environmental challenge: removing and destroying per- and polyfluoroalkyl substances (PFAS), commonly called "forever ...

As the global population grows, fresh water supplies are more precious than ever. While scientists and engineers know how to purify water, making those methods sustainable and energy efficient is ...