Nature

Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases

Innovative approaches to controlled nucleobase-modified RNA synthesis are urgently needed to support RNA biology exploration and to synthesize potential RNA therapeutics. Here we present a strategy ...
Nature

Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro

While evolution is often considered from a DNA- and protein-centric view, RNA-based regulation can also impact gene expression and protein sequences. Here we examine interspecies differences in ...
Quanta Magazine

Cells Across the Tree of Life Exchange ‘Text Messages’ Using RNA

Long known as a messenger within cells, RNA is increasingly seen as life’s molecular communication system — even between organisms widely separated by evolution. For a molecule of RNA, the world is a ...
Labroots

From Transcriptomes to Epigenomes: Introduction to single-cell RNA-seq and single-cell ATAC-seq

Single-cell technology has revolutionized the field of biological research by enabling the analysis of individual cells, providing unprecedented insights into cellular heterogeneity and function. More ...
mccormick.northwestern.edu

ES_APPM 372: Introduction to the Analysis of RNA Sequencing Data

This course will give an introduction to the theory and practice of analyzing high-throughput RNA sequencing through lectures and hands-on exercises. The basic topics covered will include: 1) the ...