Background Double sequential defibrillation (DSD) is a promising treatment for patients with out-of-hospital cardiac arrest ...

When a new treatment becomes available for a particular health condition, such as a new medication to treat a disease, it's tested to see whether it's effective for its intended purpose. It's also ...

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise ...

Randomized, open-label, multicenter, controlled study of galeterone vs enzalutamide in men with metastatic castration-resistant prostate cancer (mCRPC) expressing AR-V7 splice variant (ARMOR3-SV).

Would you volunteer to become vegetarian for the next three decades for the sake of science? What if you were asked to run at least 50 kilometres per week, or live through a natural disaster? Granted, ...

Importance Structured communication tools and decision aids are recommended to facilitate goals of care discussions (GOCDs) in hospitalised patients, but their impact remains unclear. Objective To ...

Clinical trials are under way around the world, including in Australia, testing COVID-19 vaccines and treatments. These clinical trials largely fall into two groups. With observational studies, ...

A cluster randomised trial (CRT) is a randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be ...

Randomised phase 3 trial of enzalutamide in first line androgen deprivation therapy for metastatic prostate cancer: the ANZUP ENZAMET Trial (ANZUP 1304). This is an ASCO Meeting Abstract from the 2015 ...