High-throughput sequencing relies on mechanical and enzymatic techniques to break apart DNA into fragments in a consistent and reliable manner. However, traditional approaches tend to favor DNA ...

In this report, we present OLAF-Seq, a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. We use the CRISPR-Cas9 nickase ...

Genotyping is essential to quantitative and population genetic studies, as well as genomics-assisted breeding in crops and animals. Innovations in DNA sequencing technology over the past decades have ...

Whole genome sequencing (WGS) is a ubiquitous laboratory technique with applications in drug development, genetic disease diagnosis, and personalized medicine. Researchers who use this valuable tool ...

This article is based on a poster originally authored by Dagmara Wanda Lewandowska, PhD, Marc Gasser, PhD, Vanina Haunreiter-Dengler, PhD and Eva Meszaros, PhD, which was presented at ELRIG Drug ...

Whole genome analysis plays a critical role in the development of life-saving diagnostics, therapeutics, and vaccines, with growing interest in noncoding regions and Whole genome analysis plays a ...

16S metagenomic sequencing enables targeted exploration of microbial communities by combining amplification of the 16S ribosomal RNA (rRNA) gene, a reliable phylogenetic marker, with next generation ...

New technologies advance scalable library normalization for high-throughput genomics labs and improved amplification accuracy for oncology-focused sequencing workflows where data quality is critical ...