Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...
Spatial transcriptomics (ST) technologies have transformed our understanding of cellular organization but are limited by sparse signals and restricted gene coverage. To address these challenges, we ...
Recent advances in single-cell sequencing and spatial multi-omics have transformed our ability to resolve tumor ecosystems at unprecedented resolution.
Single-cell RNA sequencing (scRNA-seq) provides high-resolution insights into cellular heterogeneity but remains costly, restricting its use to small cohorts that often lack comprehensive clinical ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...
The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...
The single-cell genomics industry does not stop advancing, with a steady stream of new companies, kits, acquisitions, and more. One new company, ArgenTag, was founded in Argentina during the COVID-19 ...
Over the past decades, lineage tracing has been fundamental to unraveling how diverse cell types arise during development and how tumors evolve ...