We introduce FAMSA2, an algorithm that produces high-accuracy multiple-protein-sequence alignments at high speed. Across structural, phylogenetic and functional benchmarks, FAMSA2 matches or exceeds ...

Signal-to-noise. A high signal-to-noise ratio is important for achieving single-nucleotide resolution in sequencing. A lower current noise level can be attained by mutating a lysine residue in a ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...

New research headed by scientists at the Centre for Genomic Regulation (CRG) has demonstrated how the three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...