Inherited retinal degenerations are a diverse group of genetic disorders that result in progressive vision loss. Advances in ...

This Review reports on a series of recent discoveries that have added to the characterization of the molecular and cellular basis of primary immunodeficiencies (PIDs) in humans. A total of more than ...

Mendel's famous laws of heredity, established over a century ago, may not be as universal as once thought. A recent study on ...

Digenic inheritance (DI) is the simplest form of inheritance for genetically complex diseases. By contrast with the thousands of reports that mutations in single genes cause human diseases, there are ...

There were distinct patterns of elevated dN/dS across the Campanulaceae depending on functional category and gene/gene family (Figure 4). For example, genes involved in gene regulation only exhibited ...