Moreover, BAP1-acquired biallelic mutations are frequent in human cancers8,11,12,13,14. BAP1 tumour suppressor activity has been attributed to its nuclear localization, where it helps to maintain ...
6Beijing Engineering Research Center of Targeted Drugs and Cell Therapy for CNS Tumors, Beijing, PR China. 7China National Clinical Research Center for Neurological Diseases, Beijing, PR China.
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Each compound generated a distinct pathway-level signature, even under identical exposure conditions. These results indicated that human hepatic organoids reflect functional hepatocellular injury ...
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