As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...

In the study of bacteria, a longstanding dogma has held that two molecular machines—RNA polymerase, which leads the way in transcribing DNA into RNA, and ribosomes, which bring up the rear translating ...

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells. Specifically, the code ...

Originally developed to track gene transfer through bacterial conjugation, the system uses an engineered ribozyme (an RNA strand capable of catalyzing specific biochemical reactions) that inserts a ...

Hiroshima University researchers have demonstrated a proof of concept for the mass production of genome-edited T cells that ...

Since its molecular structure was deduced in the 1950s, DNA has been hailed by many biologists as the secret of life. They’ve read and studied the information stored in the DNA found in the cells of ...

Summary: The physical migration of newborn nerve cells through the developing brain causes widespread, severe DNA damage. Researchers discovered that as migrating neurons squeeze through crowded, ...

You will be redirected to our submission process. The Fanconi anaemia DNA repair pathway safeguards genome stability by resolving DNA inter-strand crosslinks and replication stress; its loss promotes ...

Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal part of brain development.

How did scientists determine that DNA is the hereditary material? Groundbreaking experiments by Griffith, Avery, Hershey, and Chase disproved the notion that proteins were genetic material. Through a ...