Exploration means looking around, observing, describing and mapping undiscovered territory, not testing theories or models. The goal is to discover things we neither knew or expected, and to see ...

Colorectal cancer (CRC) remains one of the most heterogeneous malignancies, with substantial variability in molecular ...

The GeneTitan® family of instruments and proven GeneChip® Array Plates from Thermo Fisher Scientific are the first to provide a hands-free, automated solution for monitoring gene expression and genome ...

Scientists at ETH Zurich have identified a compound that sharply reduced nerve-cell death in mice engineered to develop ...

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...

Abstract: In the diagnosis and treatment of cancer, cancer classification is a vital issue. Gene selection is much needed to solve the high dimensionality issue in microarray data, small sample size, ...

RIKILT-Institute of Food Safety, Wageningen UR, Business Unit Bioanalysis & Toxicology, Akkermaalsbos 2, 6708 WB Wageningen, The Netherlands Division of Toxicology, Wageningen University and Research ...

† ∥ † Key Laboratory of Systems Biomedicine (Ministry of Education) and ∥ School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People’s Republic of China ‡ Shanghai Municipal ...

Background Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the 4p16.3 region. Seizures are frequently, but not always, associated with WHS.

Genes that follow similar expression trajectories in response to stress or stimulus tend to share biological functions. Thus, it is reasonable and common to cluster genes by expression trajectories.