Researchers led by developmental biologist Kathy Niakan at the University of Cambridge have used base editing in human embryos to learn more about human embryonic development. By deactivating a gene ...

A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...

Multimodal spatiotemporal atlas to reveal CCDC3+ CAFs as drivers of liver metastasis in colorectal cancer. Inetetamab combined with pyrotinib for neoadjuvant treatment of HER2-positive locally ...

Over the last one hundred years, the discovery of new viruses has been a gradual process. Viruses were described one by one using a suite of techniques such as electron microscopy and viral culture.

Disclaimer: This code was written inside the Genomics England Research Environment without github and it has not been tested outside the research environment. We provide it here to aid the ...

The class Mollicutes (trivial name “mycoplasma”) encompasses a large group of bacteria having no cell-wall and a minute size genome (580 to 2,200 kb). From an evolutionary point of view, Mollicutes ...

† Biomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, Christchurch, New Zealand ‡ Department of Chemistry, University of Canterbury, Christchurch, New Zealand ...

[Nature Medicine, 2022] AI in health and medicine. paper [GitHub, 2024] dna-claude-analysis: Personal genome analysis toolkit using Claude to analyze raw DNA data across 17 categories (health risks, ...

The categories are fully described elsewhere 46, and included conserved regions 47, USCC gene models (exons, introns, promoters, UTRs), and functional genomic annotations constructed using data from ...