The use of microarrays to analyse gene expression on a global level has recently received a great deal of attention. There has been much speculation about the power of this approach in the analysis of ...

Although there is only one human genome sequence, different genes are expressed in many different cell types and tissues, as well as in different developmental stages or diseases. The structure of ...

Colorectal cancer (CRC) remains one of the most heterogeneous malignancies, with substantial variability in molecular ...

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...

Dr. Lue Ping Zhao is a biostatistician with a background/experience in bioinformatics, epidemiology and genetics. He aims to accelerate the translation of big data technologies and findings to ...

Researchers at Cima and Clinica Universidad de Navarra have identified new molecular mechanisms underlying multiple myeloma. This type of hematologic cancer, which affects the bone marrow, is ...

Scientists at ETH Zurich have identified a compound that sharply reduced nerve-cell death in mice engineered to develop ...

Introduction Fibroblastic foci represent the cardinal pathogenic lesion in idiopathic pulmonary fibrosis (IPF) and comprise activated fibroblasts and myofibroblasts, the key effector cells responsible ...

Background Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the 4p16.3 region. Seizures are frequently, but not always, associated with WHS.

Researchers at the University of California San Diego have developed a large-scale screening approach that identifies ...

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...

As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...