Small-molecule switches put therapeutic CRISPR editing under on-demand control in living tissues

In a study published in Science Translational Medicine, a team of researchers led by Dr. Wang Yu from the Shenzhen Institutes ...
Health Affairs

Three Interventions That Reduce Childhood Obesity Are Projected To Save More Than They Cost To Implement

Policy makers seeking to reduce childhood obesity must prioritize investment in treatment and primary prevention. We estimated the cost-effectiveness of seven interventions high on the obesity policy ...
BMJ Open

Protocol for the economic evaluation of integrated longitudinal public health interventions in a cluster randomised controlled trial setting: the healthy life trajectories ...

Introduction In 2021, globally, cardiometabolic diseases (CMDs) accounted for 35% of the 1.73 billion disability-adjusted life years (DALYs) attributed to non-communicable diseases. The Healthy Life ...
eLife

TopoMetry systematically learns and evaluates the latent geometry of single-cell data

A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...