Optimizing RNA design with AI and an Ising machine: Encoding matters

RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene ...

AI unlocks previously invisible cortical lesions in MS using legacy MRI scans

One of the uncomfortable truths about multiple sclerosis is that the part of the brain likely to reveal the most about the ...

Elusive Alzheimer's protein aggregates missed by current tests revealed with molecular imaging technology

A molecular imaging technology developed by Prof. Shai Rahimipour of Bar-Ilan University is helping scientists uncover one of ...
The Lancet

Inherited retinal degenerations: clinical phenotypes and emerging therapies

Inherited retinal degenerations are a diverse group of genetic disorders that result in progressive vision loss. Advances in ...
eLife

Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
Europe PMC

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

We conducted gene set analysis that compared the major depression GWA results to targets of antidepressant medications defined by pharmacological studies 58, and found that 42 sets of genes encoding ...