RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene ...

MitoCareX Bio completes comprehensive SLC transport protein analysis to support discovery of small molecules for hard-to-treat cancers and inflammatory metabolic diseases and enters an AI-driven small ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

pggb builds pangenome variation graphs from a set of input sequences. A pangenome variation graph is a kind of generic multiple sequence alignment. It lets us understand any kind of sequence variation ...

This important study addresses the problem of detecting weak similarity between protein sequences, a procedure commonly used to infer homology or assign putative functions to uncharacterized proteins.

Edit distance—a classical problem in computer science—has received ongoing attention from both practitioners and theoreticians. Given two strings A and B, the edit distance is the minimum number of ...

In 2022, a team of computer scientists presented a groundbreaking algorithm for the maximum flow problem: How does one transport the most supplies from a source node to a sink node in a network while ...

parasail is a SIMD C (C99) library containing implementations of the Smith-Waterman (local), Needleman-Wunsch (global), and various semi-global pairwise sequence alignment algorithms. Here, ...

Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, Illinois 61081, United States Department of Bioengineering, University of Illinois ...

SNAP is a program that is part of a gene sequencing pipeline. It takes data from gene sequencing hardware that consists of short chunks of DNA (typically 70-300 base pairs long) called reads and ...