Tooth loss affects billions worldwide. A Kyoto University spinout is testing a drug called TRG-035 that could regrow real ...

Japanese biotech drug aims to reverse tooth loss by regrowing teeth. Here's how TRG-035 works, where trials stand and when it ...

The interaction between Hertwig's epithelial root sheath (HERS) and surrounding mesenchymal cells is crucial for root dentin formation. HERS influences tooth root development and odontoblast ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Teeth function not only because of the hard enamel on the surface, but also because they have roots that anchor them firmly in the jawbone beneath the gums. Eating, speaking, and maintaining the shape ...

A drug targeting the USAG-1 protein entered human trials in Japan in 2024. Researchers aim to make third tooth regrowth ...

Scientists are uncovering a surprising link between hidden tooth infections and blood sugar problems. Deep infections around tooth roots can create chronic inflammation that spreads through the body ...

Sometimes, a tooth can become so severely damaged or infected that your dentist might discuss a couple of different kinds of treatment plans with you. The first is a root canal, and the other is a ...