proActiv is an R package that estimates promoter activity from RNA-Seq data. proActiv uses aligned reads and genome annotations as input, and provides absolute and relative promoter activity as output ...
This study introduces Phantasus, a useful tool accessible through both web and local applications, designed to analyze transcriptome data derived from microarray or RNA-seq technologies. The ...
Biological function in protein complexes emerges from more than just the sum of their parts: Molecules interact in a range of different subcomplexes and transfer signals/information around internal ...
Integrative bioinformatics analysis to identify the effects of circadian rhythm on Crohn’s disease
Background: Crohn’s disease (CD) is a multifactorial inflammatory bowel disease characterized by complex aberrant autoimmune disorders. Currently, the involvement of the circadian rhythm in the ...
Objective: The aim of the study was to use a network pharmacological method to examine the mechanism of Guishao-Liujun decoction against gastric cancer (GC). Methods: The traditional Chinese medicine ...
We developed NEUral-network based Cell Annotation, NeuCA, a R/Bioconductor tool for cell type annotation using single-cell RNA-seq data. It is a supervised cell label assignment method that uses ...
1Graduate School of Public Health & Health Policy, City University of New York, New York, New York. 2Institute for Implementation Science in Population Health, City University of New York, New York, ...
The RTS,S malaria vaccine is the most advanced malaria vaccine candidate to be tested in humans. Despite its promise, there is little understanding of its mechanism of action. In this work, we ...
The Cancer Genome Atlas (TCGA) project has generated abundant genomic data for human cancers of various histopathology types and enabled exploring cancer molecular pathology per big data approach. We ...
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