Two-photon light sheet microscopy offers great potential for a range of biological applications, but its practical implementation is impeded by the high cost of laser sources, the complexity of ...

National Laboratory of Solid-State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210093, People’s ...

Modern technologies designed for tissue structure visualization like brightfield microscopy, fluorescent microscopy, mass cytometry imaging (MCI) and mass spectrometry imaging (MSI) provide large ...

Studies of bacterial communities, biofilms and microbiomes, are multiplying due to their impact on health and ecology. Live imaging of microbial communities requires new tools for the robust ...

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-shifting interferometer, built onto a phase-contrast microscope, with white-light illumination. As one of ...

Cells don’t operate in isolation. They constitute and reside in highly complex, interconnected tissue systems. They exert biological influence on their surroundings and are functionally differentiated ...

Usiigaci, ウシーガチ, ushi:gachi in Hepburn romanization, in Ryukyuan language means "tracing", "透き写し" in Japanese，i.e. drawing the outline of objects based on a template. The process is essentially what ...

Multiwavelength digital holographic microscopy (DHM) has been used to improve phase reconstructions of digital holograms by reducing 2π phase ambiguities. However, most samples used as test images ...

Shortening timelines to generate more productive, stable, and high-expressing cell lines is the goal of any cell line development program. Here, we explore the advantages of combining of a technology ...

Some organisms have adapted to natural sunlight, while others (e.g., rhizosphere microbiomes) have evolved in darker conditions. Yet, modern microscopy requires higher light levels than natural ...

Imaging flow cytometry combines the high-throughput capabilities of conventional flow cytometry with single-cell imaging. Here we demonstrate label-free prediction of DNA content and quantification of ...