Many cancer-associated mutational signatures remain unexplained. Team CAUSE aims to connect DNA damage, mutational patterns, ...

Cellular senescence occupies a pivotal position in cancer biology, acting as both a barrier against malignant transformation and a potential driver of ...

Scientists have long known that heat can be used to help fight cancer. But heating tumors and cancer cells is trickier than ...

Scientists have uncovered a molecular switch that could explain why colorectal cancer becomes far more dangerous once it ...

A new "tumor-on-a-chip" model is giving scientists a live look at how pancreatic cancer can recruit the body's own immune ...

Scientists have identified a molecular switch that may help explain how colorectal cancer becomes deadly. When levels of a ...

Cancer immunotherapy drugs known as immune checkpoint inhibitors (ICIs) can be miracle drugs for cancer patients, curing some and turning deadly disease into a manageable chronic condition in others.

Psychological stress may alter the gut microbiome, potentially accelerating the aging process in bone marrow stem cells, a ...

A new study has demonstrated that colon cancer cells may change identity to metastasize. Loss of GATA6, a transcription factor that controls which genes are turned on or off, can reprogram colorectal ...

Background Sociodemographic inequalities impact patients with non-small cell lung cancer (NSCLC). Advances in novel ...

A research team at the University of Turku in Finland has developed a reliable laboratory model to study BAP1-deficient ...

Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell ...