Nanoparticles introduced into the bloodstream encounter the immune complement system, a proteolytic cascade that bridges innate surveillance and adaptive responses. Complement activation can occur via ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

IIT Kanpur scientists have unlocked the mystery behind the C5aR2 immune receptor's unique function. Using advanced cryo-EM, ...

New research has uncovered a hidden pathway that allows COVID-19 to infect the immune system and trigger damaging ...

SAN DIEGO -- There was a clinically meaningful reduction in proteinuria with iptacopan (Fabhalta), and a confirmed clinical benefit of alternative pathway inhibition, in a rare kidney disorder, ...