Background Ivacaftor is the first cystic fibrosis transmembrane conductance regulator (CFTR) modulator demonstrating clinical benefit in patients with cystic fibrosis (CF). As ivacaftor is intended ...

Large observational datasets are often used in epidemiology or social sciences to identify risk factors associated with health outcomes. However, these studies can be misleading when the putative risk ...

eDepartment of Internal Medicine, School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands fDivision of Human Nutrition and ...

Background Social welfare policies such as the minimum wage can affect population health, though the impact may differ by the level of unemployment experienced by society at a given time. Methods We ...

Although dietary fiber is widely recommended for preventing and treating functional constipation (FC), clinical trial evidence remains limited and the efficacy has not been sufficiently tested in ...

Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) are associated with an increased risk for breast cancer, and CHIP is associated with increased ...

Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, 1090 Vienna, Austria Vienna Doctoral School in Chemistry (DoSChem), University of Vienna, ...

Correspondence to Mr K Bhaskaran, London School of Hygiene and Tropical Medicine, M107, 49–51 Bedford Square, London WC1B 3DP, UK; Krishnan.Bhaskaran{at}lshtm.ac.uk Context: While the effects of ...

Although smoking cigarettes has been shown to have a protective effect on preeclampsia, quitting smoking also results in weight gain. Weight gain leading to an obese body mass index is a risk factor ...

aDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK bThe National Hospital for Neurology and Neurosurgery, Queen Square, London, UK The development ...

Multiphase Chemistry Department, Max Planck Institute for Chemistry, Hahn-Meitner-Weg 1, 55128, Mainz, Germany Article Views are the COUNTER-compliant sum of full text article downloads since November ...