LRP2 is a scalable, end-to-end long-read proteogenomics pipeline built in Nextflow. It identifies and validates protein isoforms by integrating PacBio long-read RNA-seq with mass spectrometry.
The rapid evolution of high-resolution mass spectrometry (MS) has necessitated the development of increasingly sophisticated proteomics software to translate complex spectral data into biologically ...
kentsislab/proteomegenerator3 is a bioinformatics pipeline that can be used to create sample-specific, proteogenomics search databases from long-read RNAseq data. It takes in a samplesheet and aligned ...
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Sample preparation for single-cell proteomics is generally performed in a one-pot workflow with multiple dispensing and incubation steps. These hours-long processes can be labor intensive and lead to ...
Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr.-Bohr-Gasse 9, 1030 Vienna, Austria Center for Molecular Biology, Department of Biochemistry and Cell Biology, University ...