Single-cell RNA-seq AI analysis has become the default way to make sense of the millions of expression measurements a single experiment can now generate. Turning raw sequencing counts into ...

pggb builds pangenome variation graphs from a set of input sequences. A pangenome variation graph is a kind of generic multiple sequence alignment. It lets us understand any kind of sequence variation ...

The longevity effects of drugs like Rapamycin are more like a “biological lottery” with their benefits varying widely between individuals, a new study finds. A key aim of such drugs is not only to ...

Abstract: Consensus of a network with a directed acyclic graph, a directed graph with no directed cycles, is always guaranteed if it contains a spanning tree. This paper studies the effect of adding ...

This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2024. Many real-world networks change dynamically but can be notoriously ...

One of the oldest power plants in the United States, perched on the edge of the nation’s largest coal mine, was slated to close in 2027. But the plant’s operator recently canceled the retirement of ...

More than 90 percent of Fortune 500 companies use open-source products, reflecting the important role they play in the economy. Business leaders and policymakers have puzzled over how to motivate and ...

Molecular profiling technologies, such as RNA sequencing, offer new opportunities to better discover and understand the molecular networks involved in complex biological processes. Clinically ...

Introduction Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth ...