C&EN

Assessing the Interactions between Snake Venom Metalloproteinases and Hydroxamate Inhibitors Using Kinetic and ITC Assays, Molecular Dynamics Simulations and MM/PBSA-Based ...

Rua Conde Pereira Carneiro 80, Dept. de Pesquisa e Desenvolvimento, Fundação Ezequiel Dias, Belo Horizonte 30510-010, Minas Gerais, Brazil ...
IEEE

Designing High-Performance Mismatched Filters for Radar Applications

Abstract: This paper addresses the problem of computing optimal mismatched filter coefficients for various radar waveforms such as linear frequency modulation (LFM), Barker code (BC), Zadoff-Chu (ZC) ...
PNAS

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

DNA methylation and histone modifications are two key epigenetic mechanisms in regulating gene expression, heterochromatin assembly, and genome stability. In mammals, maintenance of DNA methylation is ...
PNAS

Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri

Shigella flexneri, a gram-negative bacterium, is the major culprit of bacterial shigellosis and causes a large number of human infection cases and deaths worldwide annually. For evading the host ...