Electrical and Computer Engineering Department and Physics Department, Boston University, Boston, Massachusetts 02215, and Istituto di Chimica del Riconoscimento Molecolare, CNR, Milano, Italy * To ...

aCentre for Individualised Infection Medicine (CiiM), A Joint Venture Between the Helmholtz Centre for Infection Research (HZI) and the Hannover Medical School (MHH), Hannover, Germany bTWINCORE, A ...

Previous EWASs (Epigenome-Wide Association Studies) have reported hundreds of blood pressure (BP) associated 5′-cytosine-phosphate-guanine-3′ (CpG) sites. However, their results were inconsistent.

• Can simultaneously detect the impact of several metabolites. • Does not directly translate into changes in protein activity due to restrictions to protein-metabolite binding; It is worth mentioning ...

We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with ...

Di (2-ethylhexyl) phthalate (DEHP), is the most common member of the class of phthalates that are used as plasticizers and have become common environmental contaminants. A number of studies have shown ...

We describe the first, to our knowledge, integrated dynamic DNA nanotechnology and 2D material electronics to overcome current limitations for the detection of DNA single-nucleotide polymorphism (SNP) ...

The histone variant H2A.Z is a universal mark of gene promoters, enhancers, and regulatory elements in eukaryotic chromatin. The chromatin remodeler SWR1 mediates site-specific incorporation of H2A.Z ...

Cell-free DNA (cfDNA) testing for fetal trisomy is highly effective among high-risk women. However, there have been few direct, well-powered studies comparing cfDNA testing with standard screening ...

DNA methylation is the most studied epigenetic modification, capable of controlling gene expression in the contexts of normal traits or diseases. It is highly dynamic during early embryogenesis and ...

Inflammation has been closely linked to auto-immunogenic processes in atherosclerosis. Plasmacytoid dendritic cells (pDCs) are specialized to produce type-I interferons in response to pathogenic ...