APOB-100 (apolipoprotein B100) is the obligate structural protein of very low-density lipoprotein (VLDL), intermediate density lipoprotein, and low-density lipoprotein (LDL), with each atherogenic ...

Dissecting the functions and the regulatory mechanisms of intracellular phase separation is fundamental to understanding transcriptional control, cell fate transition and disease development. However, ...

The following sample code creates two synthetic datasets, and calculates and visualizes their persistent homology to showcase the use of TDAstats. Calculation of persistent homology: the C++ Ripser ...

Deeper understanding of T-cell-mediated adaptive immune responses is important for the design of cancer immunotherapies and antiviral vaccines against pandemic outbreaks. T-cells are activated when ...

Actin-depolymerising factors (ADF) are a known family of proteins that regulate actin dynamics. Actin regulation is critical for primitive eukaryotes since it drives their key cellular processes.

Quantifying and comparing complex spatial biological datasets is crucial for medical applications and remains an active area of research. As datasets become more heterogeneous and complicated, so must ...

Homology modelling has matured into an important technique in structural biology, significantly contributing to narrowing the gap between known protein sequences and experimentally determined ...