As genome editing therapies move through clinical trials to regulatory approval, scientists continue the quest for the holy ...

In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have now uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become ...

The revolution in genome editing by CRISPR-Cas9 – a bacterial adaptive immune system against foreign pathogenic DNA molecules like plasmids and phages – has become one of the most contested landscapes ...

Unquestionably, we will emerge from this revolutionary period with modified views of components of cells and how they operate, but only, however, to await the emergence of the next revolutionary phase ...

bDepartments of Child Health, Neurology, and Cellular & Molecular Medicine and Program in Genetics, University of Arizona College of Medicine, Phoenix, AZ, United States cDepartment of Genetics, ...

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It has been 70 years since Barbara McClintock discovered transposable elements (TE), and the mechanistic studies and functional applications of transposable elements have been at the forefront of life ...

Conotruncal defects due to developmental abnormalities of the outflow tract (OFT) are an important cause of cyanotic congenital heart disease. Dysregulation of transcriptional programs tuned by NKX2-5 ...

Department of Molecular Compound Physics, Center for Physical Sciences and Technology, Savanorių 231, Vilnius LT-02300, Lithuania Vilnius University, Life Sciences Center, Institute of Biotechnology, ...

Since 1859, when Charles Darwin’s On the Origin of Species was first published, the theory of natural selection has dominated our conceptions of evolution. As Darwin understood it, natural selection ...

Pseudogenes have been considered as non-functional genes. However, peptides and long non-coding RNAs produced by pseudogenes are expressed in different tumors. Moreover, the dysregulation of ...