Language-based screeners may miss kids who struggle to read due to visual-processing issues

Reading difficulties, like dyslexia, are common and often affect achievement and outcomes during school and later in life. A ...
Frontiers

Multi-scale data reveal a CD24(+) MUCL1(+) tumor subgroup associated with unfavorable prognosis in ER+ breast cancer

Breast cancer remains the leading cause of cancer-associated death for women globally. For the group of ER+ breast cancer patients, there are still some problems of poor prognosis that need to be ...
ahajournals.org

Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial

Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) patients with heart failure and preserved left ventricular ejection fraction assigned to spironolactone ...
Nature

Clinical and pathological analysis of colonic Crohn's disease, including a subgroup with ulcerative colitis-like features

Little is known regarding the clinical and, in particular, pathological manifestations of patients with isolated colonic Crohn's disease. The purpose of this study was to evaluate the clinical and ...
PNAS

Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival

We begin with a data matrix from diseased tissue, in which columns are patients and rows are any genomic variable type, for example transcriptional microarray data. We assume we have tumor data ...
The Lancet

Multiplicity in randomised trials II: subgroup and interim analyses

Copyright: © 2005 Elsevier Ltd. Published by Elsevier Ltd. Subgroup analyses can pose serious multiplicity concerns. By testing enough subgroups, a false-positive ...