LAPIS: A Phase III Randomized, Placebo-Controlled, Double-Blind Trial of Neoadjuvant Pamrevlumab With Chemotherapy for Patients With Locally Advanced Pancreatic Cancer This single-arm study at the ...

Silvertown is changing drastically. From the mid-19th century until the early 1980s, riverside factories and quayside warehouses occupied the former marshes here. Since the closure of most of its ...

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondria biogenesis and cell stress playing a role in metabolic and degenerative diseases. In the ...

Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous syndrome. Phenotyping patients into pathophysiologically homogeneous groups may enable better targeting of treatment.

When a patient with advanced HF is referred to a transplant center, the initial evaluation requires an assessment of the severity of HF, the identification of any potentially reversible factors, and ...