David Baker’s research team at the Institute for Protein Design has unveiled a new technique for sequestering membrane ...

The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.

For many people, "protein" is the key element of a food order. However, beyond the preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose ...

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

Green fluorescent protein has an iconic structure. National Institute of General Medical Sciences/National Institutes of Health via Flickr, CC BY-NC Fruit flies, mice, zebra fish, yeast and the tiny ...

Abstract: The analysis of molecular cavities, where ligands interact with protein structures, plays a critical role in protein structure-based drug design. However, it is a challenge because of the ...

🧬 Extract SAE features from protein language models (PLMs) 📊 Analyze and interpret learned features through association with protein annotations 🎨 Visualize feature patterns and relationships 🤗 ...

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The ...