This trial is the first large, placebo-controlled clinical trial of an acid suppression treatment in EoETopline results for the double-blind 12-week treatment portion of the study are expected in Q4 ...

Introduction: Patients with Class II, division 1 malocclusion generally seek treatment to improve facial esthetics. Therefore, the orthodontist needs to know the changes in the soft profile produced ...

The study enrolled 110 nonvalvular persistent AF patients aged 18 to 80 years with left atrial diameters <50 mm, randomized to PVI alone or PVI plus roof line ablation. Patients were randomized 1:1 ...

Abstract: We present a practical approach to intercompare a range of candidate digital elevation models (DEMs) based on predefined criteria and a statistically sound ranking approach. The presented ...

Continuous sciatic popliteal nerve block effectively manages pain after ankle and foot surgery. Most studies on continuous infusion of local anesthetics by perineural catheters have been made with ...

Benefit from cardiac resynchronization therapy (CRT) varies by QRS characteristics; individual randomized trials are underpowered to assess benefit for relatively small subgroups. The authors analyzed ...

Opioid-based anesthesia is a traditional form of anesthesia that has a significant analgesic effect; however, it can cause nausea, vomiting, delirium, and other side effects. Opioid-free anesthesia ...

A randomized controlled trial was conducted in a single oncology clinic in western Kenya (NCT03404297). A computer-generated randomization schedule was used to allocate treatment arms. Randomized ...

Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient This investigator-initiated, ...

A closed-loop system of insulin delivery (also called an artificial pancreas) may improve glycemic outcomes in children with type 1 diabetes. A total of 101 children underwent randomization (78 to the ...

The ethical practice of research requires researchers to give reasons and justifications for their actions, both to the other members of their research team as well as to external audiences. We ...