Rock Paper Shotgun

Here's your NYT Connections hint for Tuesday Jun 30

Our Connections hints guide provides daily hints, tips, and answers to help you solve today's Connections puzzle on Tuesday, ...
GitHub

A pipeline for homology based annotation utilizing exon structural conservation

Dependencies: python (inlcuding numpy, ete3, pandas, and intervaltree libraries), HMMER version 3, MAFFT. Wise2 is also required to use the "full_pseudoexon_search ...
GitHub

guide.md

So you want to write a Lisp interpreter? Welcome! The goal of the Make-A-Lisp project is to make it easy to write your own Lisp interpreter without sacrificing those many "Aha!" moments that come from ...
ahajournals.org

Super-Enhancer–Driven HCG20 Promotes Pulmonary Hypertension Through U2AF2 Splicing

Pulmonary artery endothelial cell (PAEC) dysfunction is a pathological hallmark of pulmonary hypertension (PH). Yet, the roles of long noncoding RNAs (lncRNAs) driven by super-enhancers (SEs) in PAECs ...
Frontiers

Characterization and neurogenic responses of primary and immortalized Müller glia

Primary Müller glia (MG) have been reported to exhibit a neurogenic capacity induced by small molecules. However, whether immortalized mouse MG cell lines exhibit neurogenic capacities similar to ...
PNAS

Molecular insights into de novo small-molecule recognition by an intron RNA structure

The ability to target and regulate RNA function with small molecules has vast potential, but molecular understanding of the metrics governing RNA–drug interactions is limited. Here, we present a ...