parasail is a SIMD C (C99) library containing implementations of the Smith-Waterman (local), Needleman-Wunsch (global), and various semi-global pairwise sequence alignment algorithms. Here, ...

This package contains Python bindings for parasail. Parasail is a SIMD C (C99) library containing implementations of the Smith-Waterman (local), Needleman-Wunsch (global), and semi-global pairwise ...

This study provides an important computational tool for analyzing and deconvoluting a pool of plasmids sequenced without barcoding using nanopore long-read sequencing. The tool, which has been ...

Extracellular matrices direct the formation of mineral constituents into self-assembled mineralized tissues. We investigate the protein and mineral constituents to better understand the underlying ...

This valuable paper presents a new protocol for quantifying tRNA aminoacylation levels by deep sequencing. The improved methods for discrimination of aminoacyl-tRNAs from non-acylated tRNAs, more ...

Sequence alignment is a key component of bioinformatics pipelines to study the structures and functions of proteins, and to annotate open reading frames in newly sequenced genomes and metagenomes 1.

Single-cell Hi-C (scHi-C) analysis has been increasingly used to map chromatin architecture in diverse tissue contexts, but computational tools to define chromatin loops at high resolution from scHi-C ...

To evaluate the result generated by the ZSDP approach against standard sequence alignments, we compared the genome annotation files with RNA-seq results using Cufflinks v2.2.1 (Trapnell et al., 2012).

It was a double shock on The Apprentice this week as resident 'pantomime villain' Selina Waterman Smith was fired and Scott Saunders sensationally quit the show. Week nine saw the eight remaining ...