Researchers at the University of Liverpool have identified distinctive biological characteristics within adenomyosis lesions ...
A new multiplex immunofluorescence workflow using standard laboratory equipment and open-source software enables detailed ...
A new development in data science has given one popular machine learning tool an improved sense of place, enabling it to make ...
The heart and brain are among the earliest and most metabolically demanding organs in human development. Though historically studied in isolation, both ...
Arsenic and other metalloids are among the most pervasive and toxicologically significant contaminants of agricultural soils and irrigation waters. Their ...
We developed a statistical method for Integrative and Reference-Informed Spatial Domain Detection for Spatial Transcriptomics. IRIS is a reference-informed integrative method for detecting spatial ...
Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...
Background Most patients with biliary tract cancer (BTC) do not derive durable clinical benefit (DCB) from immune checkpoint inhibitors (ICIs), underscoring the urgent need for predictive biomarkers.
Abstract: The spatial context of single-cell gene expression data is crucial for many downstream analyses, yet often remains inaccessible due to practical and technical limitations, restricting the ...
Efficacy and safety of disitamab vedotin combined with toripalimab for cisplatin-refractory advanced penile cancer: A prospective single-center study (SAVE). HRS-1167 (M9466), a PARP1 inhibitor, ...
A detailed description of the pipeline, methods, and results can be found in the following article: Giraud-Sauveur, F., Blampey, Q., Benkirane, H. et al. STHELAR, a multi-tissue dataset linking ...
Chikungunya virus, which is transmitted to people by infected Aedes mosquitoes and characterized by high fever and intense joint swelling and pain, has made a resurgence in many countries around the ...