Colorectal cancer (CRC) remains one of the most heterogeneous malignancies, with substantial variability in molecular ...

Research led by RCSI University of Medicine and Health Sciences and University College Dublin (UCD) has identified immune markers that could help doctors more accurately determine which breast cancer ...

Triple-negative breast cancer (TNBC) is a heterogeneous and aggressive form of breast cancer with diverse clinicopathological and biological behavior. Classified as “triple-negative” due to the lack ...

4 Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 5 Department of Gastroenterology and Hepatology, National University Health System, Singapore 6 ...

Beyond its already established respiratory symptoms, COVID-19 is now recognized as a systemic disease with widespread effects, including significant neurological impact. During the acute phase of ...

Abstract: Accurate identification of ovarian cancer subtypes from histopathological images is crucial for guiding treatment, but remains challenging. We present a deep learning approach to classify ...

1 Translational Research Program, Public Health Sciences Fred Hutchinson Cancer Research Center, Seattle, Washington, USA 9 Great Lakes New England (GLNE) Clinical Validation Center of EDRN, ...

Abstract: We present a geometry-driven graph learning framework for histopathology that converts Tissue Microarray (TMA) images into Delaunay triangulation graphs of superpixels. Unlike ...

Chromosome 1q23.3 is commonly amplified in metastatic urothelial carcinoma (UC). This region contains NECTIN4 that encodes for a membrane protein, and amplification may result in increased NECTIN4 ...

Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...

The Fibroblast growth factor receptors 3-transforming acidic coiled-coil-containing protein 3 (FGFR3-TACC3, F3-T3) oncogenic fusion gene, identified in malignant tumors such as gliomas and bladder ...

Prediction of Adjuvant Gemcitabine Sensitivity in Resectable Pancreatic Adenocarcinoma Using the GemPred RNA Signature: An Ancillary Study of the PRODIGE-24/CCTG PA6 Clinical Trial We performed ...