This package will be useful to anybody who wants to infer graphical models for all sorts of compositional data, though primarily intended for microbiome relative abundance data (generated from 16S ...

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Genome-wide association studies (GWAS) are crucial for identifying numerous single nucleotide polymorphisms (SNPs) linked to various diseases. However, current methods struggle with regional ...

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Estimate a mixture model with a Poisson or negative binomial count model and a point mass at zero. The predictors can be different for the two models. The estimated model can be saved and used for ...

Joint Species Distribution Models (JSDM) have received a lot of attention in the last decade as they provide a general multivariate framework to study the joint abundances of all species from a ...

Single cell RNA sequencing (scRNA-seq) allows quantitative measurement and comparison of gene expression at the resolution of single cells. Ignoring the batch effects and zero inflation of scRNA-seq ...